What does SILEO do to dogs? Sileo is a medicine prescribed by your veterinarian. It helps calm your dog when frightened by loud noises around your home without making them drowsy. Sileo is different from other medicines: The first of its kind—SILEO is the first FDA-approved treatment for noise aversion in dogs.
How long does it take for SILEO to kick in? The drug takes effect after approximately 30 minutes to one hour. Your dog should show less intense noise aversion behavior, despite the ongoing noise. Some dogs might be more sensitive to the drug; if your dog appears drowsy, keep it warm and do not offer food or water until the effect of the drug has worn off.
Is SILEO gel a sedative? The active substance in Sileo, dexmedetomidine hydrochloride, is a type of sedative medicine called an alpha-2 adrenoceptor agonist. It works by preventing the release of the neurotransmitter noradrenaline from nerve cells in the body.
How long do the effects of SILEO last? The effects of SILEO® last about 2-3 hours, so the storms are usually over well before it wears off. But for those rare occasions when the thunder occurs throughout the day, we love that it’s safe to keep giving it to Chilly every 2 hours, up to five times during the day.