What does cyclosporine do for dogs?

What does cyclosporine do for dogs? Cyclosporine for dogs, also known by the brand names Atopica and Optimmune, is an immunosuppressant drug mostly used to treat atopic dermatitis. This condition is not contagious, but it causes chronic inflammation of the skin due to an overactive immune system response.

How Long Can dogs stay on cyclosporine? The recommended dose of Cyclosporine is it should be given initially as a 5 mg/kg/day (3.3-6.7 mg/kg/day) single daily dose for 30 days.

Is cyclosporine the same as Apoquel? Atopica® (cyclosporine) and Apoquel® (oclacitinib) are separate and distinct medications. Both are used for controlling the signs and symptoms of atopic dermatitis (“allergies”) in dogs. They are two of the most effective allergy treatments for dogs.

What are the side effects of cyclosporine? 

Common side effects of cyclosporine include:
  • High blood pressure.
  • Increased hair growth.
  • Swollen or inflamed gums.
  • Numbness or tingling of the hands or feet.
  • Other common side effects are tremors, restlessness, stomach upset, nausea, cramps, diarrhea, headache, and changes in blood sugar.

What does cyclosporine do for dogs? – Additional Questions

Is cyclosporine A high risk medication?

Taking cyclosporine or cyclosporine (modified) may increase the risk that you will develop an infection or cancer, especially lymphoma (cancer of a part of the immune system) or skin cancer.

How quickly does cyclosporine work?

Cyclosporine can provide rapid relief from symptoms. You may see some improvement in symptoms after two weeks of treatment, particularly with stronger doses. However, it may take from three to four months to reach optimal control. Extended use of cyclosporine by transplant patients is well-established.

What medications should not be taken with cyclosporine?

Cyclosporine may interact with other medications
  • Antibiotics. Taking cyclosporine with certain antibiotics may lead to an increased risk of kidney damage.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Antifungals.
  • Acid reflux drugs.
  • Birth control drugs.
  • Immunity-suppressing drug.
  • High cholesterol drugs.
  • Blood pressure drugs.

Who should not take cyclosporine?

cancer or malignancy. high cholesterol. high amount of triglyceride in the blood. low amount of magnesium in the blood.

Does cyclosporine make you gain weight?

Yes, prolonged consumption of cyclosporine can lead to a gain in weight. Cyclosporine affects a patient’s appetite because of which there may be either weight gain or weight loss. However, only rare cases of weight change have been reported so far.

How does cyclosporine affect the kidneys?

The cyclosporine group demonstrated reductions in glomerular filtration rate and renal plasma flow, with higher renal vascular resistance and mean arterial pressure as compared with an azathioprine-treated control group.

Can cyclosporine be stopped abruptly?

You should consult your doctor before you stop taking this medicine or before you change the amount for any reason. You may become ill if you stop taking this medicine suddenly. You may want to take cyclosporine with some food if the medicine upsets your stomach.

Is cyclosporine hard on the kidneys?

Cyclosporine is a very strong medicine. It can cause side effects that can be very serious, such as kidney problems. It may also decrease the body’s ability to fight infections.

Is there a substitute for cyclosporine?


Is Cyclosporine a steroid?

Cyclosporine is a steroid-sparing agent, which is safer to use topically for prolonged periods of time,” Dr. Jeng said. In fact, a few patients were completely weaned from steroids.

Is there a generic version of cyclosporine?

The U.S. Food and Drug Administration has approved the first generic of Restasis (cyclosporine ophthalmic emulsion) 0.05% single-use vials (eye drops) to increase tear production in patients whose tear production is presumed to be suppressed due to ocular inflammation associated with keratoconjunctivitis sicca (

Does cyclosporine weaken immune system?

Cyclosporine works by suppressing the immune system to prevent the white blood cells from trying to get rid of the transplanted organ. Cyclosporine is also used to treat severe rheumatoid arthritis in patients who have failed treatment with methotrexate.

Can cyclosporine cause liver damage?

Cyclosporine therapy can be associated with mild elevations in serum bilirubin and transient serum enzyme elevations, and to rare instances of clinically apparent cholestatic liver injury.

Is cyclosporine an anti inflammatory?

Introduction: It is well known that cyclosporin A (CsA) exhibits important anti-inflammatory effects, besides its immunosuppressive activity.

Is cyclosporine A chemotherapy?

RATIONALE: Some cancers become resistant to chemotherapy drugs. Combining cyclosporine with chemotherapy may prevent resistance to the drugs and allow the cancer cells to be killed.

Condition or disease Intervention/treatment Phase
Leukemia Drug: cyclosporine Drug: etoposide Drug: mitoxantrone hydrochloride Phase 2

Why is cyclosporine hazardous?

Section 2 – Hazards

Cyclosporin A (also known as cyclosporine) is a potent immunosuppressant that may be harmful if ingested, inhaled, or absorbed through the skin. It may cause irritation to the gastrointestinal tract, respiratory tract, skin, and eyes.

How do you wean off cyclosporine?

Dose tapering schedules were every other day and twice weekly. After the 4-week induction period at 7 mg/kg, the dose could be tapered to every other day in 70% of cats while still maintaining clinical remission. Up to 57% could have the dose tapered to twice weekly.